CD86 and CD80 Differentially Modulate the Suppressive Function of Human Regulatory T Cells
نویسندگان
چکیده
منابع مشابه
CD86 and CD80 differentially modulate the suppressive function of human regulatory T cells.
Regulatory T cells (Treg) are important in maintaining tolerance to self tissues. As both CD28 and CTLA-4 molecules are implicated in the function of Treg, we investigated the ability of their two natural ligands, CD80 and CD86, to influence the Treg-suppressive capacity. During T cell responses to alloantigens expressed on dendritic cells, we observed that Abs against CD86 potently enhanced su...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2004
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.172.5.2778